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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fbaf4776015cf5cbcc104a5eb8c7c08aad578bb5a10434f6dbf0e76baa37904' 
  AND token = 'cP4n3Ocz5PBumvsVZG8n4yKo7/oR5NrYgQElmyZZS7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}