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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4490a99aacbd8b32c614257790b392179a56eae6ad8357a7e3af1d485486c4' 
  AND token = 'FgrI4l4a/0wnlbvBN/5RYJxKLo0TBHrtIrL2xC6wrJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}