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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b25b693b9ee6548e4f33edec9c4f29a7b459b8e20872b259e608087247f4e6' 
  AND token = 'U/MU5UB1Fa5+nS4XW1NcUaYC16kscr5CszRpQYdiqX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}