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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65914794d0db703b147c6964bb9ce8bbe59e9c9215598a1545a18e1fecdf840b' 
  AND token = '57Bp7yI/VVuQHwtwtidNHhH+B1UQEszFzD0KkxNhwuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}