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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77990bb070bf896a4040f0dfc0f2ce2b216560a8b51f5bcedb20250b6c4ba9f1' 
  AND token = 'hbOryWt390bityEN8l99AtHC13fZaHcXb09tD0V4PNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}