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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7278046f613344bf7262613b6884b3665079c1261a7c636e4546f9fbb5606b72' 
  AND token = '4XJebEe8eLxMaWdHAs/7tlZCY8rGjV8h1HYFPFLM+tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}