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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cd191d69ff1ab82bbe882b6c3ecfedace6a5d8d858a3f3f6ef797b2a1312a0' 
  AND token = '+B8OGDIFnxCfDGWFC+oRaW2hPzAeaQqEhlQYkzfM0PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}