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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321e56deba3380764e6daf3c19a467733ed5a4dc2bbe7ab21a4e565cef4f7ead' 
  AND token = 'ZjT2IIMMGWW2Rx1R3qnT6KueHHiuSNBIeT4QvshVABk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}