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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7391395ae06dc97e1e9041f784171195a8fde0fcf37338d9895b19b45b45f557' 
  AND token = '6i5USew0rmxyjTgD3nSO7gLeuRoJCylcjQKDTs2+0Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}