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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e041661bd2d50c6148083cf008b5cbaeb91950b1dc594bc9450a26e759daa6' 
  AND token = '/SGg7aEpxBoEUmDJoDT9AqHZqYMLFb+eUN5aOMMw080=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}