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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2187af0e605f547f960e353592cfb4180f91e436f1ec1fed418d0cad379f04d0' 
  AND token = '4ofYzvm9yZfEZSC9bNqgNoSFqPJDez0W7VNJPF2rHTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}