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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b010e8d8f55dc8540e80b64f75dad39607c65a160ff697f9bc006c9d396e8f6a' 
  AND token = '+gcbRoDIrZ0n3hqIf5k3JscnthZ/5P6uunnigXAGpqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}