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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a360cc83bb3cf7015ae92c9186dd9df9f45a5e6aec2a4b851dbfd178f5a978c4' 
  AND token = 'oNhrWpAPv3gN76/KrayhaKOOqgS6c7HF9ShBisq6Auo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}