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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e0bd0f24885f6db7f8b1ec52bbb5feb1a89c21338a9c48f01fbae7155e0b9c' 
  AND token = 'KY7zHQSI/ynnQRh5FTL5PvA7kLR/yEEFBQ1L33ScHBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}