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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff36249920962a6a9f44f84c5e63c289c3856a3760d2f9a3f73898def3831c9' 
  AND token = 'jfJ5ebPG74EIyFBoaIejSQ+0In81sdtKLZM6RFPWMzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}