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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba084c634546bd2d568f5f215d4faa2c4333dca6f0d5462dab8b2e3a1c043df' 
  AND token = 'B0V0PXEQuhqEMtc4v6a8IlYRnzmkGfw3P70ZlhRHiLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}