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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a0a40c4eff06a39125a0ae1b11143cfb545181071a30ffbbdc32f27a4733f33' 
  AND token = 'CMAVykdtQmIil1XyGLt0tbK3r+VyFEnSbxZ/qPCyP7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}