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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fb6ff66c385fa93a29e1b1e48608271b5a9953a7c49ffab76422a25db89006b' 
  AND token = 'rs2/Bx6TCvZCJ+0Tdsorob0L4PBDgwtGV3Ti3WfSjR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}