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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2e583cb9afdb0b9c0f8e04bce13b4344407449e202b384be115501ecb5e639' 
  AND token = 'PI9qeeHqByS9wEwEKmsCT6q1PlLSf4Wr6Ho33z9xIN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}