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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba43221a399ac71fb096c27e6c1eaf6c09fedbafa008d372e13a89612057ae2' 
  AND token = 'D91fiBIzxzdCDjX3ZHKzpPfWGHCJ7CjiEPodd7Ku/2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}