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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc82288f0278f95919c6046accf4bd0e312659907c161ee2f02ea70f36b26f2' 
  AND token = 'PTIKZq0CFqvoNFiMgNLLmrAENN2FYn/H0uyvllEdgzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}