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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c734ce11a91a2400333b57691b7c85315c7b19af92a5b767e7b564d22db6b947' 
  AND token = 'gtupWgye3VWNAxx20ll3bKmmJ5cqtfRHQu5WY4GbxQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}