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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5108d1e24d577af475872f6bba0ee7568823c44689b919f3b423b07b0bb462f' 
  AND token = 'qTzrgDQ0mmJIR/m0kxWuJsx+QfdC1bafF8S2UWL8Ww4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}