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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2caa82c18134e460039209e54d60712ba2d8ea2c62c8af67e485841239d032' 
  AND token = 'SmVXTSqGTxUzFDBZTrt+lNVD3RtnxD+TpBPL0YJu5cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}