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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffff4884d4886ed9ede80665459fb5e845a98bceae2edf64a8e11757fc9cc08f' 
  AND token = 'Jvxf4Um7dvM66Tlor2NQxAkE6CAnZV3mZpZhQHe05ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}