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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241b98add0c35cc029e16d4d5a842677e389ab8d29d90249d6aae0a086f70d3f' 
  AND token = 'jN2SP9P7OpTOgwuUJhAyffp/moFeWzMduUOw0Q7Bsg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}