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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d608d2d988ff0237768cf77cc81540b299210bf6b6aaf4556a65d89ce85596' 
  AND token = 'UpOhmBT+uev7sO3cUeODd6Pfw9tdHA6BnNq3McaPbDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}