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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df8a4bf93aea12d223edde3f600b20b81dfb83f4fbb806f7716a1f4e0e41253' 
  AND token = 'Hxigai5ay+O8/9vyhnQwnbBLh6hw9os1rdV2VTRsw8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}