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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4323bd94a37c1d964960debf447b410d5e87343c0737774ce0376bd538c056' 
  AND token = 'gGChIjQ7IMkEwlvQplRsP68t+WA2yrHa+JiQixrlpos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}