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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c496cd9a58e4a138e12454c1b6d28a3cd7d3b660f8342790c6db92efe0e6b267' 
  AND token = 'iuuSl7RpDBdTCM6i7cLMiWQf06/KyrN4mDGsIPqJr6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}