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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4f38128a1a9f624ed6db58814d622689ba99835121e5554565e5887ca6ca70' 
  AND token = 'T1+bDQYDKmsxfDLQ2CcDeM9zX+qz/i3FJ1dPenroci8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}