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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e999b5886bcc8341f17b8ae982eb1cd253b10dfe2dcd260d3b429752adfbf8b7' 
  AND token = 'DIxtwASvnjmXuy3m+FPkgPgX6NhTC89rQEOLMSUV2rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}