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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8916350b60388e23aebc8523940e2421df69de98324ca2cdf508eb4734434d' 
  AND token = 'Rz7ogJYgR1MMCER9Szx2+dzkfINpso4ZSS3P+kIm1CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}