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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6a804a27938055f497bc0f239f795e88595163445eceec230a3fc669ec0e7a8' 
  AND token = 'ywAJ9voB44D0RJsm3AFAXMqCg1DBC3ypb2d+424QeHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}