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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b13262378caba3e3c46d303b09c142e337802752400fb1de1761adbc4307e46' 
  AND token = 'zm81IdRGrAMbUdDbfuHnZ9pjFtcqPqQKuNggeLVMA0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}