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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d32fccb31b0bdc1a170f98681b4245dccc9ba779afe5ab3505935c3e52d6f6' 
  AND token = 'SpN3u24rt9xMmj+DmuTuKT56buKgnbkVa6nW5aFyDbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}