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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b9cb71294d0b5d06884c62a5874135d869ea8a06712775b5c007a152111fdd' 
  AND token = '7Ju0yAORR+s9+jYW6X/+eM1W+kwGU4dMp0vj0dWvtyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}