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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5669043487d32eda8a84ef57af85f1d4bdf398a0613cb5345af22ec204798c45' 
  AND token = '5CPUuLCsuWPbqmNp3lPp7rwSzBU9kzXVkiNw7wmLwwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}