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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b42ab27d2bdf0c8732bbf4e126a01ab7d401a760a1d56694aa52224890d5f16' 
  AND token = 'eO0bT1odq+u6VN21BtAvpTekCPUk0NTG4P2ebl+UDrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}