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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a56389233602cb07f1b2bbcd0254e8dec787a1ecbf310f20e96eba4d39096cd9' 
  AND token = 'UUo9WY1CHORRbFw1qxZ46Q+4aBrHSLFF6vtzmXm+XWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}