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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922608c0808ded57c729c061e471c90e9525ce530409e33b445b0eef1385b48a' 
  AND token = 'WuePt3iuYnNd2HOhHquKndyBD+x6Gj3uQ56WxYyiUpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}