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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a41136e3da40078d6b1a932294b843bd23f22cd75a27c0b4f116985a598662c' 
  AND token = 'zIPw86ac/3cRyUr1uzCPhOrSBwVlagFRECZh6qh1P00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}