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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7ca2ab280c862e1d60544029e44e3757289a7ca80dd31653ddef0aa330d7874' 
  AND token = 'd6dLnqNkTTKtG7uhjCyUxam9T4NfoLnjWMVo2Uymhxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}