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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50cadcd081e0ee7b0acba734c4ea9cddf2e5e84fd56daafb80a92275b6a32c35' 
  AND token = 'wJVuaPRwtiefvCntg5o4Th3JJD2w2s7bugMb3ilqtPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}