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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17790a0c696053b295950c8023d8499e83ba611e022d98bbb8913f5c02ade722' 
  AND token = 'w7nYiOls+rya0sBAb7YmtGBL/T27C1YvHzRY1ICgqOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}