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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a00f7039b4c7b736aedc6048865cdcfffb2dac3f3bbc5bdc7f0ac51f0972700' 
  AND token = 'MSNbu8wdJpHR61AecmyDp3ta6YSjHhZlh8EO/tmT7vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}