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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36cd794ef9ff01c01a0e2e1c58b94c8c2477618959d3088ea71b5aca99fbd8d1' 
  AND token = 'mnCJrEvLyQvkLp7XKM8gSJS4Qm1VakHJQa/2+fY2V38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}