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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c62a17e40e20ba9dea5cbbc9828005453006f48df577e4ee2fde5b293f4e2e' 
  AND token = 'ILXI5eFrsDEM465mF6HAUpP+QEiKL21ETX/Lu+11PGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}