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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f28da12967451ac936985473f0ffa8c8c3165dc659c4a657733b8fad645dd55' 
  AND token = 'wKW9a4MfYTl8kE+d5nZ9oqit6+sNwuaQvN9ySQ6qnSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}