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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9d0d037a4988cb9cc73c9c25aa80da0d079206582ac9294e97f054161cd589' 
  AND token = 'mxTUWIO6wWo7qfOaiNY2jZEq+w5JxXme6cArH2nsIk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}